I keep a box of nitrile gloves on my workbench—and anywhere else I'm likely to handle chemicals, dry or wet. They are not absolute protection, and if you notice them expanding, they aren't keeping out whatever you are handling. As protection from solvents, nitrile (and latex) are only partially effective. If you think the solvent is getting through them, it probably is. If that happens, chuck the glove ASAP, wash the hand, and use another glove.
As for touch sensitivity: surgeons use them. You can get used to it and compensate. Be sure to get a size that fits tightly if tactile sense is critical.
I wear them when spray painting, and when applying decals, when using epoxy resin, and when doing a lot of sanding, wet or dry, especially of resins.